American Society for Biochemistry and Molecular Biology
1083-351X
weekly
0021-9258
2024
8006542452
United States
English
YES
Google Scholar
jbc@elsevier.com
A journal of the American Society for Biochemistry and Molecular Biology. The Journal of Biological Chemistry (JBC) welcomes high-quality science that seeks to elucidate the molecular and cellular basis of biological processes. Papers published in JBC can therefore fall under the umbrellas of not only biological chemistry, chemical biology, or biochemistry, but also allied disciplines such as biophysics, systems biology, RNA biology, immunology, microbiology, neurobiology, epigenetics, computational biology, 'omics, and many more. The outcome of our focus on papers that contribute novel and important mechanistic insights, rather than on a particular topic area, is that JBC is truly a melting pot for scientists across disciplines. In addition, JBC welcomes papers that describe methods that will help scientists push their biochemical inquiries forward and resources that will be of use to the research community.
Notch signaling plays a complex role in carcinogenesis, and its signaling pathway has both tumor suppressor and oncogenic components. To identify regulators that might control this dual acti...
1. A study is presented of the measurement of proteins with the Folin phenol reagent after alkaline copper treatment. The basic reactions have certain peculiarities which need to be taken in...
The alkaline phosphatase of the serum increases early and markedly in rickets and returns completely to normal only after healing is complete. Because of this fact, serum phosphatase is the ...
This is a record of the concentrations of the nonenzyme components of the Embden-Meyerhof system in mouse brain measured at brief intervals after the production of complete ischemia by decap...
Conditions for the reduction of phosphomolybdic acid to molybdenum blue were established, under which labile phosphate esters were not readily hydrolysed. The procedure was based on the redu...
Elucidation of the biochemistry of the brain is hindered by its extreme histological complexity. However, if it were possible to perform appropriate chemical analyses and enzymatic measureme...
It was desired to measure a variety of enzyme activities in very small amounts of brain (10 y wet weight or less) as part of a study of the quantitative histochemistry of brain. Existing ana...
In the preceding paper (1) are recorded the concentrations in mouse brain of the substrates and cofactors of the Embden Meyerhof pathway, and the changes in concentration when the glycolyti...
Measurement of DPNH’ or TPNH by absorption at 344 rnp has been a standard procedure for many years and has been used to study innumerable enzyme reactions. In spite of the proved value of ...
In 1935 Negelein and Haas described a method for the determination of glucose 6-phosphate dehydrogenase activity based on measurement of the rate of reduced triphosphopyridine nucleotide for...
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