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About

I am a biomedical research scientist, who aims to advance knowledge and innovation in regenerative medicine. My focus is on reverting aged cells to a potent state to enable tissue regeneration. And also use these cells as human disease models for drug testing, discovery, and personalized medicine. At this moment, I am working on human Cancer and Cornea-derived blindness to reverse delayed wound healing in diabetic patients and tumorgenesis.

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Skills

Experience

Post Doctoral Scientist

Cedars-Sinai Medical Center

Mar-2022 to Present
Junior Research Fellow - Senior Research Fellow

The Centre for Cellular & Molecular Biology (CCMB)

Apr-2016 to Oct-2016
Post Doctoral Scientist

Cedars-Sinai Medical Center

Dec-2020 to Feb-2022
Teaching and Research Assistant

Sandor Lifesciences Pvt Ltd

Aug-2015 to Apr-2016

Education

Sapienza University of Rome

PhD in Molecular Medicine

Passout Year: 2020
The Central University of Rajasthan (CURaj)

MSc (Biotechnology) in Biotechnology

Passout Year: 2015
Mahatma Gandhi Kashi Vidyapith

Bsc., in Biotechnology

Passout Year: 2013

Publication

Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3

Statsignal transducer and activator of transcriptionPBSTphosphate-buffered saline tween-20PBSphosphate-buffered salineEMSAelectrophoretic mobility shift assayEGFRepidermal growth factor rece...

Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3

Statsignal transducer and activator of transcriptionPBSTphosphate-buffered saline tween-20PBSphosphate-buffered salineEMSAelectrophoretic mobility shift assayEGFRepidermal growth factor rece...

MicroRNA and Protein Cargos of Human Limbal Epithelial Cell-Derived Exosomes and Their Regulatory Roles in Limbal Stromal Cells of Diabetic and Non-Di...

Epithelial and stromal/mesenchymal limbal stem cells contribute to corneal homeostasis and cell renewal. Extracellular vesicles (EVs), including exosomes (Exos), can be paracrine mediators o...

Novel azetidine-based STAT3 inhibitors induce misfolded protein response, endoplasmic reticulum stress and mitophagy, and inhibit breast tumor growth ...

Anticancer drugs that directly target Signal Transducer and Activator of Transcription (Stat)3 have remained elusive. We present azetidine-based small molecules as a new class of potent Stat...

Novel potent azetidine-based compounds irreversibly inhibit Stat3 activation and induce antitumor response against human breast tumor growth in vivo

Signal transducer and activator of transcription (Stat)3 is a valid anticancer therapeutic target. We have discovered a highly potent chemotype that amplifies the Stat3-inhibitory activity o...

Functional cooperation between ASK1 and p21Waf1/Cip1 in the balance of cell-cycle arrest, cell death and tumorigenesis of stressed keratinocytes

Both CDKN1A (p21 Waf1/Cip1) and Apoptosis signal-regulating kinase 1 (ASK1) play important roles in tumorigenesis. The role of p21 Waf1/Cip1 in attenuating ASK1-induced apoptosis by various ...

PLK1 targets NOTCH1 during DNA damage and mitotic progression

Notch signaling plays a complex role in carcinogenesis, and its signaling pathway has both tumor suppressor and oncogenic components. To identify regulators that might control this dual acti...

DNA Damage Stress: Cui Prodest?

DNA is an entity shielded by mechanisms that maintain genomic stability and are essential for living cells; however, DNA is constantly subject to assaults from the environment throughout the...

Role in Research Journals

Conference/Seminar/STTP/FDP/Symposium/Workshop

Conference
  • dott image May 2023

ARVO Annual Meeting

Hosted By:

The Association for Research in Vision and Ophthalmology (ARVO) ,

New Orleans, Louisiana, United States
Webinar
  • dott image Apr 2023

Certified Peer Reviewer Course

Hosted By:

Elsevier Researcher Academy ,

Los Angeles, California, United States

Certificates

Issued : Nov 2023
  • dott image By : Linkedin
Project Management Foundations: Requirements

Membership

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European Association for Cancer Research (EACR)

From year to
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The Association for Research in Vision and Ophthalmology (ARVO)

From year to

Honours & Awards

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BITP
Awarded by:

DBT-BCIL

Year: 2015

Scholar9 Profile ID

S9-032024-1900891

Publication
Publication

(8)

Review Request
Article Reviewed

(0)

Citations
Citations

(0)

Network
Network

(1)

Conferences
Conferences/Seminar

(2)