About
Based on her scientific contributions, in 2009, Dr. Shaw was recognized with the Simon Dack Award for academic excellence from the American College of Cardiology and, in 2013, the Coalition to Reduce Disparities in Cardiovascular Disease Outcomes Award for her research contributions in racial and ethnic differences in cardiovascular disease. In 2013, she received the Woman’s Day Red Dress Award for her scientific contributions to women’s health. In 2020, she was awarded the Bernadine Healy Leadership in Women’s Cardiovascular Disease Award from the American College of Cardiology. Also, in 2020, she received the Nanette Wenger, MD Award from the American Society of Preventive Cardiology, and the Distinguished Investigator Award from the Academy for Radiology and Biomedical Imaging Research. Dr. Shaw is a Past President of the American Society of Nuclear Cardiology and the Society of Cardiovascular Computed Tomography. She is the only individual having served as president of two medical societies within cardiovascular medicine. Dr. Shaw has extensive experience in the conduct of clinical research with more than 1,000 peer-reviewed publications and presented more than 500 abstracts in major scientific meetings in the United States, Europe, Asia, and South America. This includes decades of experience in the conduct of multicenter clinical trials and registries including those evaluating prognostic implications and randomized treatment effectiveness of patients with stable coronary artery disease. She recently served as the PI of the Imaging Coordinating Center for the NIH-NHLBI-sponsored International Study of Comparative Health Effectiveness with Medical and Invasive Approaches (U01HL10556-01) trial, which organized imaging data for ~300 medical centers around the world. As well, she served as PI for several multicenter registries funded by NIH-NHLBI including the Computed Tomographic Evaluation of Atherosclerotic Determinants of Myocardial Ischemia trial (R01HL118019) and examination of atherosclerotic plaque progression among patients with and without infection with the severe acute respiratory syndrome coronavirus-2 (NIH-NHLBI R01HL159433). She was recently funded by NIH-NHLBI to support multiparametric, cardiovascular magnetic resonance imaging to understand mechanisms of post-intervention benefit in the percutaneous or surgical repair In mitral prolapse and regurgitation trial for ≥60 Year Olds (U01HL088942 NHLBI Administrative Supplement, Shaw, sub-PI). Dr. Shaw has been ranked as one of the top 1% of clinical researchers with the most highly cited publications (awarded by Thomson Reuters), with an H-index >153.
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Publication
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July, 2021
Rationale and design of the Women's Ischemia Trial to Reduce Events in Nonobstructive CAD (WARRIOR) trial
Background Approximately half of all women with anginal symptoms and/or signs of ischemia and no obstructive coronary artery disease (INOCA) referred for coronary angiography have elevated ...
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March, 2020
Association of Sex With Severity of Coronary Artery Disease, Ischemia, and Symptom Burden in Patients With Moderate or Severe Ischemia: Secondary Anal...
Importance While many features of stable ischemic heart disease vary by sex, differences in ischemia, coronary anatomy, and symptoms by sex have not been investigated among patients with mo...
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February, 2019
Impact of Abnormal Coronary Reactivity on Long-Term Clinical Outcomes in Women
Background: Currently as many as one-half of women with suspected myocardial ischemia have no obstructive coronary artery disease (CAD), and abnormal coronary reactivity (CR) is commonly fo...
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September, 2018
Sex differences in calcified plaque and long-term cardiovascular mortality: observations from the CAC Consortium
Aims Pathologic evidence supports unique sex-specific mechanisms as precursors for acute cardiovascular (CV) events. Current evidence on long-term CV risk among women when compared with ...
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July, 2017
Quality and Equitable Health Care Gaps for Women: Attributions to Sex Differences in Cardiovascular Medicine
The present review synthesizes evidence and discusses issues related to health care quality and equity for women, including minority population subgroups. The principle of “sameness” or ...
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May, 2017
Inflammatory biomarkers as predictors of heart failure in women without obstructive coronary artery disease: A report from the NHLBI-sponsored Women�...
Background Women with signs and symptoms of ischemia, no obstructive coronary artery disease (CAD) and preserved left ventricular ejection fraction (EF) often have diastolic dysfunction and...
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September, 2016
Cardiovascular Disease and 10-Year Mortality in Postmenopausal Women with Clinical Features of Polycystic Ovary Syndrome
Background: Women with polycystic ovary syndrome (PCOS) have greater cardiac risk factor clustering but the link with mortality is incompletely described. Objective: To evaluate outcomes in...
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April, 2016
Noninvasive Imaging to Evaluate Women With Stable Ischemic Heart Disease
Declines in cardiovascular deaths have been dramatic for men but occur significantly less in women. Among patients with symptomatic ischemic heart disease (IHD), women experience relatively ...
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November, 2015
A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and my...
Aims The mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction...
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July, 2013
Adverse outcomes among women presenting with signs and symptoms of ischemia and no obstructive coronary artery disease: Findings from the National Hea...
Background Women presenting with signs and symptoms of myocardial ischemia frequently have no or nonobstructive coronary artery disease (CAD). Objective This study aimed to investigate th...
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