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About

Dr. Chrisandra L. Shufelt is a women’s health internist and certified menopause practitioner with fellowship training in vascular biology and women’s health. She is chair of the Division of General Internal Medicine and associate director of the Women’s Health Research Center at Mayo Clinic. Dr. Shufelt has specific research interests in hypothalamic amenorrhea in young women its impact on immune and vascular health. She has published more than 200 articles in the area of women’s health and co-authored several scientific position statements on menopause and hormone therapy.

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Skills

Experience

Organization
Chair of General Internal Medicine

Mayo Clinic, Jacksonville

Jul-2022 to Present

Publication

A Machine Learning Approach to Classifying Self-Reported Health Status in a Cohort of Patients With Heart Disease Using Activity Tracker Data

Constructing statistical models using personal sensor data could allow for tracking health status over time, thereby enabling the possibility of early intervention. The goal of this study wa...

  • dott image November, 2019

Cardiovascular implications of gender-affirming hormone treatment in the transgender population

Transgender men and women represent a growing population in the United States and Europe, with 0.5% of adults and 3% of youth identifying as transgender. Globally, an estimated 0.3–0.5% of...

Age at Menarche and Risk of Cardiovascular Disease Outcomes: Findings From the National Heart Lung and Blood Institute‐Sponsored Women's Ischemia Sy...

Background Previous studies have reported an association between the timing of menarche and cardiovascular disease (CVD). However, emerging studies have not examined the timing of menarche ...

  • dott image February, 2018

Association of Spontaneous Preterm Delivery and Future Maternal Cardiovascular Disease

Cardiovascular disease (CVD) risk factors are well established. However, little is known about a woman’s cardiovascular response to pregnancy, which appears to be an early marker of future...

  • dott image February, 2017

Menopausal symptoms and cardiovascular disease mortality in the Women's Ischemia Syndrome Evaluation (WISE)

Objective: Studies have linked vasomotor symptoms (VMS) to markers of cardiovascular disease (CVD) risk, yet few have considered clinical cardiovascular events. Data suggest that associati...

Preeclampsia and Vascular Function: A Window to Future Cardiovascular Disease Risk

Preeclampsia affects ∼3%–7% of all pregnancies and is the third leading cause of maternal mortality globally. Growing evidence indicates that preeclampsia results from vascular dysfuncti...

  • dott image November, 2015

A randomized, placebo-controlled trial of late Na current inhibition (ranolazine) in coronary microvascular dysfunction (CMD): impact on angina and my...

Aims The mechanistic basis of the symptoms and signs of myocardial ischaemia in patients without obstructive coronary artery disease (CAD) and evidence of coronary microvascular dysfunction...

Cardiac Magnetic Resonance Myocardial Perfusion Reserve Index Is Reduced in Women With Coronary Microvascular Dysfunction: A National Heart, Lung, and...

Background— Women with signs and symptoms of ischemia and no obstructive coronary artery disease often have coronary microvascular dysfunction (CMD), diagnosed by invasive coronary reacti...

  • dott image September, 2014

A randomized controlled trial of acupuncture in stable ischemic heart disease patients

Background Heart rate variability (HRV) is reduced in stable ischemic heart disease (SIHD) patients and is associated with sudden cardiac death (SCD). We evaluated the impact of traditional...

  • dott image March, 2014

Hormone therapy dose, formulation, route of delivery, and risk of cardiovascular events in women findings from the Women’s Health Initiative Observa...

Objective Research comparing hormone therapy (HT) doses, regimens, and routes of delivery in relation to cardiovascular disease (CVD) outcomes has been limited. This study directly compare...