About
I am interested in understanding human brain network organization from neuroimaging data in health and disease. My recent methodological work has focused on graph theory to measure aspects of brain network topology. I am also interested in better neuroscientific understanding and treatment of psychiatric disorders. I am currently leading a consortium funded by the Wellcome Trust and pharmaceutical companies (GSK, Janssen, Lundbeck) - the Neuroimmunology of Mood Disorders and Alzheimer's Disease (NIMA) consortium - which is exploring immune mechanisms and therapeutics for depression and dementia. Professor Ed Bullmore came to Cambridge as a Professor of Psychiatry in 1999, after undergraduate and graduate degrees at Oxford and King's College, London, where he played a prominent role at the Institute of Psychiatry. He is one of the most distinguished research psychiatrists in the UK with an international reputation. His research mainly involves the application of brain imaging to psychiatry. He has introduced an entirely original approach to the analysis of human brain anatomy, involving graph theory and its application to small world networks. This has had an enormous impact on the field, especially in relation to understanding the biological basis of schizophrenia and depression. His work has been key to the understanding of the 'wiring' of the human brain. He was Head of the Department of Psychiatry from 2014 – 2021 and is currently Deputy Head of the School of Clinical Medicine and Director of the Wolfson Brain Imaging Centre. He has been a Vice-President at GlaxoSmithKline, researching how anti-inflammatory drugs may be used in the treatment of psychiatric disorders. His popular science book "The Inflamed Mind: A Radical New Approach to Depression” was a Sunday Times bestseller.
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Experience
Director, Research & Development
Cambridgeshire & Peterborough NHS Foundation Trust (CPFT)
Dec-2011 to Dec-2024Education
Publication
Acute effects of interferon-alpha on cellular anabolic and catabolic processes are associated with the development of fatigue during Interferon-alpha-...
Introduction Interferon-alpha (IFN-α) is a key mediator of antiviral immune responses used to treat Hepatitis-C virus (HCV) infection. Though clinically effective, IFN-α frequently induce...
Structural MRI of brain similarity networks
Recent advances in structural MRI analytics now allow the network organization of individual brains to be comprehensively mapped through the use of the biologically principled metric of anat...
Extra-axial inflammatory signal and its relationship to peripheral and central immunity in depression
Although both central and peripheral inflammation have been observed consistently in depression, the relationship between the two remains obscure. Extra-axial immune cells may play a role in...
Quantitative susceptibility mapping at 7 T in COVID-19: brainstem effects and outcome associations
Post-mortem studies have shown that patients dying from severe acute respiratory syndrome coronavirus (SARS-CoV-2) infection frequently have pathological changes in their CNS, particularly i...
Disorders of compulsivity: a common bias towards learning habits
Why do we repeat choices that we know are bad for us? Decision making is characterized by the parallel engagement of two distinct systems, goal-directed and habitual, thought to arise from t...
A bimodal taxonomy of adult human brain sulcal morphology related to timing of fetal sulcation and trans-sulcal gene expression gradients
We developed a computational pipeline (now provided as a resource) for measuring morphological similarity between cortical surface sulci to construct a sulcal phenotype network (SPN) from ea...
Evaluating Models of the Ageing BOLD Response
Neural activity cannot be directly observed using fMRI; rather it must be inferred from the hemodynamic responses that neural activity causes. Solving this inverse problem is made possible t...
Posthospitalization COVID-19 cognitive deficits at 1 year are global and associated with elevated brain injury markers and gray matter volume reduct...
The spectrum, pathophysiology and recovery trajectory of persistent post-COVID-19 cognitive deficits are unknown, limiting our ability to develop prevention and treatment strategies. We repo...
Brain, lifestyle and environmental pathways linking physical and mental health
Depression and anxiety are prevalent in people with a chronic physical illness. Increasing evidence suggests that co-occurring physical and mental illness is associated with shared biologica...
Brain charts for the human lifespan
Over the past few decades, neuroimaging has become a ubiquitous tool in basic research and clinical studies of the human brain. However, no reference standards currently exist to quantify in...
Invited Position
A New Approach to Depression
University of Cambridge
From year 2018 to 2018https://www.youtube.com/watch?v=I9DofDwJfyQ
CSAR
University of Cambridge
From year 2019 to 2019https://www.youtube.com/watch?v=Gz-qbvqQBu4
Patent
- Medical & Health Science
Methods for assessing psychotic disorders
Cambridge Enterprise Ltd
United States
May 2005
US11/990,825
US20090136423A1
Published
May 2008
Scholar9 Profile ID
S9-122024-2307479
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