About
JoAnn E. Manson, MD, DrPH, MACP, is Professor of Medicine and the Michael and Lee Bell Professor of Women’s Health at Harvard Medical School, Professor in the Department of Epidemiology, Harvard T.H. Chan School of Public Health, Chief of the Division of Preventive Medicine at Brigham and Women's Hospital (BWH), and Scientific Advisor to the BWH Connors Center for Women’s Health and Sex/Gender Medicine. Dr. Manson is a physician epidemiologist, endocrinologist, and Principal Investigator (PI) or co-PI of several research studies, including the Women’s Health Initiative Clinical Center In Boston, the cardiovascular component of the Nurses’ Health Study, the VITamin D and OmegA-3 TriaL (VITAL); the COcoa Supplement and Multivitamin Outcomes Study (COSMOS), and the VItamin D for COVID-19 (VIVID) trial. Her primary research interests include randomized clinical prevention trials of nutritional and lifestyle factors related to heart disease, diabetes, and cancer, the role of endogenous and exogenous estrogens as determinants of chronic disease, life course-related risk factors for CVD in women, and biomarker predictors of CVD. Dr. Manson has received numerous honors, including the American Heart Association’s (AHA) Population Research Prize, the AHA’s Distinguished Scientist Award, the AHA’s Research Achievement Award, election to the Institute of Medicine of the National Academies (National Academy of Medicine), membership in the Association of American Physicians (AAP), fellowship in AAAS, the Woman in Science Award from the American Medical Women’s Association, the Bernadine Healy Award for Visionary Leadership in Women’s Health, the Massachusetts Medical Society awards in both Public Health and Women’s Health Research, the James D. Bruce Memorial Award for Distinguished Contributions in Preventive Medicine from the American College of Physicians (ACP), and election to mastership in ACP. Dr. Manson has published more than 1,200 peer-reviewed articles in the medical literature, is the author or editor of several books and textbooks, serves as Editor-in-Chief of Contemporary Clinical Trials, and is a past president of the North American Menopause Society. She is one of the most highly cited researchers in the world and was one of the physicians featured in the National Library of Medicine’s exhibition, History of American Women Physicians. She received her BA from Harvard College, her MD from Case Western Reserve University School of Medicine, and an MPH and DrPH from the Harvard School of Public Health. Dr. JoAnn Manson has been a leading researcher in the two largest women's health research projects ever launched in the United States—the first large scale study of women begun in 1976 as the Harvard Nurses' Health Study, and the National Institute of Health's Women's Health Initiative, which involved 164,000 healthy women. Until the early 1990s, research on human health was usually done from all-male subject groups, and the results generated were thought to apply to both sexes. Federal regulation now mandates the inclusion of women in all research studies, as men and women may react differently to certain diseases and drug remedies, a fact Dr. Manson's research efforts have helped to establish. JoAnn Elisabeth Manson was in 1953, in Cleveland, Ohio. She comes from a strong scientific background; her mother was a medical social worker and her father worked as an engineer for the National Aeronautics and Space Administration. Her high-school chemistry teacher encouraged her to train in the sciences, yet her school friends knew her artistic side best, particularly her painting, sculpture, and musical talents playing the harp. She was able to develop all her interests at Harvard University, reviewing dance and theater for the Harvard Independent while studying pre-med. Her well-rounded approach to life and to work has earned her the respect of colleagues and patients alike. Dr. Manson is best known to the public for her sensible advice on healthy living, which stems from her research on women and heart disease. With co-author Patricia Amend, she published The 30-Minute Fitness Solution: A Four-Step Plan for Women of All Ages, which explains her key idea of the preventative health benefits of gentle exercise. She has long been advising her patients to take up small lifestyle changes for long term health benefits, recognizing that no-cost activities like brisk walking can be a simple way of improving the health of women of all backgrounds and fitness levels. She often uses her prescription pad to write up an exercise regime for a patient instead of a course of pills. Patients applaud her "bedside manner." Her medical practice serves 400 patients, yet she takes time to tailor her care to fit in with individual schedules and interests. Such attention to the individual, not simply the medical problem, has been honored by Boston Magazine who listed her as one of their "Top Docs for Women" in 2001 Dr. Manson's colleagues also credit her ability to deal with "difficult personalities" and competitive environments. Such qualities serve her well at work—in 1999 she was appointed full professor at Harvard Medical School, where women hold only 9 percent of faculty professorships. Not withstanding her own professional achievements, Dr. Manson is still well aware of the gender disparities in academic medicine. As she commented in The Houston Chronicle, "[w]omen are still confronting barriers to their success. The glass ceiling may have some cracks in it, but it hasn't yet come crashing down." Dr. Manson is playing her own part in making a change by participating in mentoring programs and giving young practitioners extensive guidance and support. She is extremely proud of the students she has helped, and lists their professional achievements in her C.V. In 1997, along with Oprah Winfrey and former First Lady Betty Ford, she was honored by American Health for Women magazine at a ceremony for their "Ten Heroes in Women's Health." Ladies Home Journal named her one of their top ten "Champions of Women's Health" in 2000. As well as her numerous roles as researcher, physician, teacher, and writer, Dr. Manson is a mother. She and her husband, Christopher Ames, try to balance work and family life with their two children.
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Experience
Education
Publication
Vitamin D Supplements and Prevention of Cancer and Cardiovascular Disease
Background It is unclear whether supplementation with vitamin D reduces the risk of cancer or cardiovascular disease, and data from randomized trials are limited. Methods We conducted a n...
Association analysis identifies 65 new breast cancer risk loci
Breast cancer risk is influenced by rare coding variants in susceptibility genes, such as BRCA1, and many common, mostly non-coding variants. However, much of the genetic contribution to bre...
Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents
Background Overweight and obesity are increasing worldwide. To help assess their relevance to mortality in different populations we conducted individual-participant data meta-analyses of pr...
Cardiovascular Disease in Women: Clinical Perspectives
Cardiovascular disease continues to be the leading cause of death among women in the United States, accounting for ≈1 of every 3 female deaths. Sex-specific data focused on cardiovascular ...
Menopausal Hormone Therapy and Health Outcomes During the Intervention and Extended Poststopping Phases of the Women’s Health Initiative Randomized ...
Importance Menopausal hormone therapy continues in clinical use but questions remain regarding its risks and benefits for chronic disease prevention. Objective To report a comprehensive...
Heart Disease and Stroke Statistics—2013 Update: A Report From the American Heart Association
Each year, the American Heart Association (AHA), in conjunction with the Centers for Disease Control and Prevention, the National Institutes of Health, and other government agencies, brings ...
The 2011 Report on Dietary Reference Intakes for Calcium and Vitamin D from the Institute of Medicine: What Clinicians Need to Know
This article summarizes the new 2011 report on dietary requirements for calcium and vitamin D from the Institute of Medicine (IOM). An IOM Committee charged with determining the population n...
Triggering of Sudden Death from Cardiac Causes by Vigorous Exertion
Background Retrospective and cross-sectional data suggest that vigorous exertion can trigger cardiac arrest or sudden death and that habitual exercise may diminish this risk. However, the r...
Postmenopausal Hormone Therapy and Risk of Cardiovascular Disease by Age and Years Since Menopause
Context The timing of initiation of hormone therapy may influence its effect on cardiovascular disease. Objective To explore whether the effects of hormone therapy on risk of cardiovascul...
Calcium/Vitamin D Supplementation and Cardiovascular Events
Background— Individuals with vascular or valvular calcification are at increased risk for coronary events, but the relationship between calcium consumption and cardiovascular events is unc...
Projects
Effects of Vitamin D and Fish Oil on the Kidney in Hypertensives
Randomized Trial of Vitamin D and Omega-3 Fatty Acids for Diabetic Kidney Disease
VITAL-DEP: Depression Endpoint Prevention in the VITamin D and OmegA-TriaL
Interrelationship of Magnesium, Vitamin D, and Cardiometabolic Outcomes in the VITAL Trial
The VITamin D and OmegA-3 TriaL (VITAL) Renewal
Randomized Trial of Cocoa Flavanols and Multivitamins for CVD and CA Prevention (COSMOS Blood)
Randomized Trial of Cocoa Flavanols and Multivitamins for CVD and CA Prevention (COSMOS)
Risk Factors for Ischemic Stroke, Renewal
Risk Factors for CVD in Women
Dietary and Hormonal Determinants of Cancer in Women (Project 2)
Honours & Awards
Best Female Scientist Award
Research.com
Year: 2024Best Scientist Award
Research.com
Year: 2024Medicine in United States Leader Award
Research.com
Year: 2024Best Female Scientist Award
Research.com
Year: 2023Distinguished Scientist Award
American Heart Association
Year: 2011Distinguished Scientist Award
American Heart Association
Year: 2011History of American Women Physicians
Bethesda, Maryland
Year: 2011top 1% most cited scientists in the world
Thomson Reuters
Year: 2011Population Research Prize
American Heart Association
Year: 2010Fellow
the Royal Society of Edinburgh
Year: 2009Henry Burger Research Prize
International Menopause Society
Year: 2008Postmenopausal Cardiovascular Health Research Award
North American Menopause Society
Year: 2007Women's Professional Achievement Award
Harvard College
Year: 2006election to membership
Association of American Physicians
Year: 2005"Women in Science" Award
American Medical Women's Association
Year: 2003Henry Ingersoll Bowditch Award for Excellence in Public Health
Massachusetts Medical Society
Year: 2002Outstanding Contribution Award & quot
WHI
Year: 1995Alpha Omega Alpha Honor Medical Society
Alpha Honor Medical Society
Year: 1978Scholar9 Profile ID
S9-012025-0808023
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