Paper Title

Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3

Authors

Profile picture of Nagendra Verma,
Nagendra Verma,
Profile picture of James Turkson
James Turkson
Profile picture of Francisco Lopez-Tapia
Francisco Lopez-Tapia

Journal

Bioorganic & Medicinal Chemistry Letters External link

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DOI

DOI Icon 10.1016/j.bmcl.2023.129565

Publication Info

Volume: 97 | Pages: 129565

Published On

January, 2024

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Abstract

Statsignal transducer and activator of transcriptionPBSTphosphate-buffered saline tween-20PBSphosphate-buffered salineEMSAelectrophoretic mobility shift assayEGFRepidermal growth factor receptor, JAK, Janus kinase, SH2, Src homology 2, MAPK, mitogen-activated protein kinaseErkextracellular signal-regulated kinaseFBSfetal bovine serum

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