Research Article

doi:10.1016/j.bmcl.2023.129565

Paper Title

Azetidine ring, salicylic acid, and salicylic acid bioisosteres as determinants of the binding characteristics of novel potent compounds to Stat3

Authors

James Turkson

Francisco Lopez-Tapia

Article Type

Research Article

Journal

Bioorganic & Medicinal Chemistry Letters

Research Impact Tools

DOI

10.1016/j.bmcl.2023.129565

Issue

Volume : 97 | Issue : 129565 | Page No : 1-7

Published On

January, 2024

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Abstract

Statsignal transducer and activator of transcriptionPBSTphosphate-buffered saline tween-20PBSphosphate-buffered salineEMSAelectrophoretic mobility shift assayEGFRepidermal growth factor receptor, JAK, Janus kinase, SH2, Src homology 2, MAPK, mitogen-activated protein kinaseErkextracellular signal-regulated kinaseFBSfetal bovine serum