Potential of New Ferulic Acid analogue and Paeonia lactiflora Roots Extract and Cellulitis Triggering Pathogens

Abstract

Facts over Escherichia coli and Staphylococcus aureus ability to trigger cellulitis, and antimicrobial potential of Paeonia lactiflora plant motivated present study to compare the inhibitory potential of ferulic acid analogue (FAA) and Paeonia lactiflora root extract (PLRE) against cellulitis triggering bacteria (CTB). Current study involved synthesis of FAA and preparation of PLRE. The PD was characterized using ATR-IR, 1H-NMR and Mass spectrometric data. Both FAA and PLRE were further investigated for their antibacterial activity against CTB namely: Escherichia coli and Staphylococcus aureus. Among two, the FAA exhibited high antibacterial activity when compared with PLRE. Based onsss the results, present study concludes that FAA possess high antimicrobial potential against CTB and recommends that FAA should be further investigated to support its clinical significance.