Abstract
In connection with certain chemical and pathological studies of various tissues, it was desired to obtain quantitative estimates of the contents of collagen and elastin. Since no completely satisfactory methods for measurement of these substances were found in the literature, the methods described here were elaborated. The procedure for measuring collagen has been useful in studying quantitatively the fibrous tissue of normal human myocardium and of the myocardium in cases of coronary arterial disease (1). The methods are also being used in a study of tissue composition; the solids of the extracellular compartment presumably consist of collagen and elastin together with the extracellular salts.
View more »