Therapy with the LHRH agonist leuprorelin acetate for paraphilias and sexually aggressive impulsive behavior
Abstract
To date, there is no published experience in German-speaking countries in the treatment of paraphilias (pedophilia, sadism) and sexually aggressive impulsive behavior with LHRH (lutein-releasing hormone) agonists. In this study, we describe 11 patients who were treated with the LHRH agonist leuprorelin acetate over a period of 12 months. During the treatment period, there were no further sexually aggressive behaviors and, according to the patients, there was a significant reduction in erection, ejaculation, masturbation, sexually deviant urges and fantasies. One patient died by suicide. Overall, LHRH agonists in combination with other therapeutic methods appear to be a promising alternative to cyproterone acetate with its possible carcinogenic effects.