Go Back Original Article May, 2000

Therapy with the LHRH agonist leuprorelin acetate for paraphilias and sexually aggressive impulsive behavior

Abstract

To date, there is no published experience in German-speaking countries in the treatment of paraphilias (pedophilia, sadism) and sexually aggressive impulsive behavior with LHRH (lutein-releasing hormone) agonists. In this study, we describe 11 patients who were treated with the LHRH agonist leuprorelin acetate over a period of 12 months. During the treatment period, there were no further sexually aggressive behaviors and, according to the patients, there was a significant reduction in erection, ejaculation, masturbation, sexually deviant urges and fantasies. One patient died by suicide. Overall, LHRH agonists in combination with other therapeutic methods appear to be a promising alternative to cyproterone acetate with its possible carcinogenic effects.

Keywords

Paraphilia Treatment Pedophilia Sexual Sadism Sexually Aggressive Behavior LHRH Agonists Leuprorelin Acetate Hormonal Therapy Sexual Impulsivity Erection Suppression Ejaculation Reduction Masturbation Reduction Deviant Sexual Urges Sexual Fantasies Suicide Risk Cyproterone Acetate Carcinogenic Effects Pharmacological Treatment Endocrine Therapy Sexual Offender Treatment Forensic Psychiatry German-Speaking Countries Clinical Study Psychopharmacology Sexology Behavioral Therapy Psychiatric Interventions Libido Suppression Sexual Health
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Volume 71
Pages 380–385
ISSN 1433-0407
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