Impact of Weight-Adapted Iodinated Contrast Media Administration on Image Quality in Abdominopelvic CT Scans

Abstract

Contrast-enhanced computed tomography (CT) remains one of the most frequently performed imaging procedures for abdominal and pelvic evaluation. However, the optimization of iodinated contrast administration according to patient weight is crucial to maintain uniform image quality and reduce contrast-related complications. This study evaluates the diagnostic efficacy of weight-adapted iodinated contrast media administration in abdominopelvic CT imaging. Methods: This prospective observational study included 300 patients undergoing abdominopelvic CT. Two contrast protocols were compared — a fixed 100 mL dose and a weight-adjusted dose (1.0–1.5 mL/kg). Quantitative image parameters including hepatic and splenic Hounsfield units (HU), signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) were recorded. Qualitative assessments of image quality and diagnostic confidence were performed by three radiologists using a 5-point scale. Results: Weight-adapted dosing resulted in improved image uniformity and enhanced parenchymal visualization. The mean liver and spleen attenuation values were 117.2 HU and 108.5 HU respectively. Image quality and diagnostic confidence both averaged 4.1. Patients with higher body mass demonstrated improved enhancement compared to fixed-dose groups. Conclusion: Individualized, weight-based contrast dosing ensures optimal diagnostic image quality, minimizes iodine use, and enhances clinical interpretation in abdominopelvic CT. The findings support the implementation of weight-adapted protocols in routine practice.