Anti-Inflammatory Activity of Dodonaea viscosa Leaves

Abstract

Inflammation is a response of vascularized living tissue to the local injury. Due The severe side effects of steroidal and non steroidal anti-inflammatory drugs evoked us to search for new anti-inflammatory drugs from the indigenous source. Hence, the present work was scrutinized to explore the anti-inflammatory activity of whole plant of Dodonaea viscosa.. The powdered leaves of D. viscosa were extracted with hydroalcohol and n-hexane successively. The anti-inflammatory activity was studied using carrageenan-induced rat paw edema at the dose of (100 and 200 mg/kg b.w. p.o.) of hydroalcoholic and n-hexane extract respectively. The hydroalcoholic extract of D. viscosa exhibited significant anti-inflammatory activity at the dose of 100 & 200 mg/kg than the n-hexane extract. Indomethacin (10 mg/kg b.w. p.o) had exhibited significant anti-inflammatory activity.