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About
Dr. Sarfaraz Alam, an Assistant Professor at The Institute of Advanced Research (IAR), holds a distinguished academic background with a Post-doctorate, Ph.D., M.Sc., and B.Sc. in Biological and Biomedical Sciences. With eight years of experience, he thrives in interdisciplinary settings, particularly in Medicinal Chemistry, Biochemistry, and Assay Biology. His expertise extends across multiple drug discovery programs, where he applies a diverse skill set to advance scientific understanding and develop innovative solutions. Dr. Alam's commitment to research excellence and collaborative work underscores his significant contributions to the field, making him a valuable asset in academia and drug discovery initiatives.
Skills & Expertise
multiple cheminformatics software
Computer-Aided Drug Design
QSAR
Cell Culture
Life Sciences
Computational Chemistry
Molecular Modeling
Molecular Dynamics
Homology Modeling
Virtual Screening
Pharmacophore Modeling
Protein Sequencing
Python (Beginner)
SQL (Beginner)
Polymerase Chain Reaction (PCR)
ADME
Molecular Biology
Research
Research Interests
Biomedical Sciences
Connect With Me
Experience
Mitacs Industrial Postdoc Fellow
Postdoctoral Researcher
- 1. Working on a project to modulate the protein corona formation on nanoparticles (NPs) via surface-functionalized antibody for cancer targeting 2. Performed enrichment analysis to find which GO terms are over-represented or under-represented 3. Protein-protein docking study to confirm the interaction of target and receptors protein 4. QSAR modeling to establish a statistically significant connection between biological activities of NPs and their physicochemical properties
Assistant Professor
Institutional Postdoctoral Researcher
- 1. Molecular modeling studies to identify the small molecule Inhibitor to prevent Insulin fibrillogenesis through drug repurposing strategy 2. Performed pharmacophore modeling to screened the anticancer compounds from large databases 3. Molecular docking studies of potential anticancer compounds and exploration of binding pocket/site residues of selected anti-cancer targets 4. Studied the adverse drug action and possible side effect of lead compounds through in-silico system pharmacology approach
Young Scientist Fellow
- 1. Conceived, developed, and conducted independent research into anticancer activity 2. Developed an online application tool to screen specific phytomolecules for anticancer lead identification. The tool can be accessed at: http://bioinfo.cimap.res.in/qlead/usermanagement/usetool.php 3. Developed multiple linear regression QSAR models for screening of phytomolecules/derivatives against human cancer cell lines/targets 4. Molecular modelling study for prediction of cytotoxic/anticancer activity of untested compounds 5. In-silico pharmacokinetics (ADMET) studies of identified anticancer compounds 6. Drafted, communicated, and published several research articles in reputed journals
Education
Council of Scientific & Industrial Research (CSIR)
Bundelkhand University, Jhansi (BU)
Bundelkhand University, Jhansi (BU)
Awards & Achievements (3)
🏆 Second Science Conclave A Congregation of Nobel laureates
Description
🏆 Young Scientist Fellow
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🏆 Mitacs Industrial Postdoctoral Fellowship
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Publications (2)
FLT3 is considered a potential target of acute myeloid leukemia therapy. In this study, we applied a computer-aided methodology unifying molecular docking and pharmacophore screening to identify poten...
As a part of our discovery of plant-based lead molecules, we provide a helpful tool, which helps in identification, designing, optimising, structural modifications, and prediction of curcumin, to disc...
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