American Association for the Advancement of Science
1095-9203
weekly
0036-8075
1925
2023266550
India
English
YES
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science_editors@aaas.org
Editor
Science has been at the center of important scientific discovery since its founding in 1880—with seed money from Thomas Edison. Today, Science continues to publish the very best in research across the sciences, with articles that consistently rank among the most cited in the world. Science Translational Medicine is an essential platform for peer-reviewed, multidisciplinary research driving the latest medical advances. Science Signaling offers original review articles, protocols and teaching resources for the growing field of cellular signal transduction. Science Immunology publishes basic, translational and clinical research specifically about immunology across all organisms and model systems, including humans. Science Robotics covers new developments in robotics and related fields, with a dual focus on the science of robotics as well as introducing researchers more broadly to how robots can be used to accelerate scientific study. Science Advances represents the next generation of online publishing, with rapid publication of significant, full-length research that is available free to readers. Science is a weekly, peer-reviewed journal that publishes significant original scientific research, plus reviews as well as commentary on current research, science policy, and issues of interest to the broad scientific community. We seek to publish papers that are influential in their fields or across fields and that will substantially advance scientific understanding. Selected papers should present novel and broadly important data, syntheses, or concepts. We welcome submissions from all fields of science and from any source.
Watching a speaker’s lips during face-to-face conversation (lipreading) markedly improves speech perception, particularly in noisy conditions. With functional magnetic resonance imaging it...
Studies of the fat-derived hormone leptin have provided key insights into the molecular and neural components of feeding behavior and body weight regulation. An important challenge lies in u...
There are significant structural changes in striatal and prefrontal brain regions of stimulant drugdependent individuals. However, it is not clear if these brain abnormalities predate drug-t...
Obsessive-compulsive disorder (OCD) is characterized by repetitive thoughts and behaviors associated with underlying dysregulation of frontostriatal circuitry. Central to neurobiological mod...
Mutations in the evolutionarily conserved codons of the p53 tumor suppressor gene are common in diverse types of human cancer. The p53 mutational spectrum differs among cancers of the colon,...
Over the past decade, comprehensive sequencing efforts have revealed the genomic landscapes of common forms of human cancer. For most cancer types, this landscape consists of a small number ...
Glioblastoma multiforme (GBM) is the most common and lethal type of brain cancer. To identify the genetic alterations in GBMs, we sequenced 20,661 protein coding genes, determined the presen...
Colon cancers with loss-of-function mutations in the mismatch repair (MMR) pathway have favorable responses to PD-1 blockade immunotherapy. In a phase 2 clinical trial, Le et al. showed that...
The characteristics of an organism are determined by the genes expressed within it. A method was developed, called serial analysis of gene expression (SAGE), that allows the quantitative and...
The adenomatous polyposis coli gene (APC) is a tumor suppressor gene that is inactivated in most colorectal cancers. Mutations of APC cause aberrant accumulation of β-catenin, which then bi...
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