Nature Biomedical Engineering brings together notable advances in applied biomedicine and health technology, and enhances their visibility by means of News & Views articles and editorials, and by providing overviews of the state of the art through topic-focused, disease-specific or technology-centred Review Articles, Perspectives and Comments. Launched in January 2017, Nature Biomedical Engineering is an online-only monthly journal publishing original research, reviews and commentary in applied biomedicine and health technology. The journal's audience include life scientists developing experimental or computational systems and methods to understand human physiology, biomedical researchers and engineers designing or optimizing therapies, assays, devices or procedures to diagnose or treat disease, and clinicians leveraging research outputs to assess patient health or deliver therapy across a variety of clinical settings and healthcare contexts.