Affiliated with the American Society for Matrix Biology and the International Society for Matrix Biology Matrix Biology was established in 1980 as Collagen and Related Research, an international scientific journal for publication of research on the extracellular matrix. The journal became Matrix (1989-1993) and then Matrix Biology in 1994 to reflect the expansion of knowledge and interest in the diversity of extracellular matrix-associated molecules and the increasing awareness of the importance of 'matrix' in development, health, and disease and its significance for biological processes. Matrix Biology is now the leading journal devoted to publishing the latest research results in extracellular matrix research that deal with molecular components of the extracellular matrix and biological impacts of cellular interactions with extracellular matrices. We welcome articles in any area of extracellular matrix research that provide new mechanistic insights or which challenge longstanding biological paradigms in the field of extracellular matrix research.