Department of Biomedical Sciences, Cedars-Sinai

The Department of Biomedical Sciences at Cedars‑Sinai is the vibrant hub where basic science and translational research powerfully combine to create solutions for medicine’s most pressing questions. We work tirelessly and collaborate across disci s. We work tirelessly and collaborate across disciplines, including immunology, imaging, genomics, neuroscience, cell biology, metabolism, bioinformatics, diagnostics and therapeutics. Under the leadership of Chair David Underhill, PhD, the Janis and William Wetsman Family Chair in Inflammatory Bowel Disease, the Department of Biomedical Sciences drives innovations that redefine the understanding of disease and result in breakthrough treatments. We bring together basic and translational researchers from across the institution to foster collaboration and new discoveries in diverse biomedical sciences. Bergman Lab ‑ Find out more about the Bergman Laboratory and their work in Diabetes and Obesity Research at Cedars-Sinai hospital in Los Angeles. Breunig Lab ‑ Cedars-Sinai researchers are studying neural stem cells to promote brain repair, understand brain tumor development, and create therapies to direct differentiation. Dey Lab ‑ The Dey Laboratory at Cedars-Sinai conducts research in the Experimental Image Analysis focuses on automated derivation of imaging measures from noninvasive cardiac image data, clinical implementation of novel automated computer processing algorithms, and the application of these tools to solve key clinical problems. Fan Lab ‑ The Fan Laboratory conducts research on the development and clinical applications of novel magnetic resonance imaging (MRI) techniques. Furuya Lab ‑ The Furuya Lab studies sphingolipid signaling in cancers and urinary biomarkers for early bladder cancer. Gao Lab ‑ The Gao Lab focuses on understanding the neurophysiological mechanisms underlying normal/abnormal human brain development and adult brain functioning. Gayther Lab ‑ Gayther Lab research focuses on identifying genetic variants that confer susceptibility to hormonal cancers and relating germ-line genetic variation to throughout the human genome. Goodridge Lab ‑ The Goodridge Research Lab led by Helen Goodridge, PhD, focuses on researching the production and diverse functions of innate immune cells known as monocytes and macrophages. Gulati Lab ‑ The Gulati Laboratory led by Tanuj Gulati, PhD is a systems neuroscience laboratory interested in understanding the motor basis of behavior. Hitchins Lab ‑ The Hitchins Laboratory undertakes translational cancer research with a focus on genetic and epigenetic alterations associated with cancer. Ho Lab ‑ Research in the laboratory of Ritchie Ho, PhD, at Cedars-Sinai aims to develop faithful models of late-onset diseases using human induced pluripotent stem cells (iPSCs) and in vivo animal models. Jones Lab ‑ The Jones Lab research spans two primary domains; improving understanding of the heritable risk for cancer, and mapping changes in the tumor genome through cancer progression to understand the mechanisms that underlie chemo-resistance and relapse. Kaye Lab ‑ Find out more about the Kaye Laboratory and its long-standing study of molecular regulation of T lymphocyte development and biology at Cedars-Sinai in Los Angeles. Knott Lab ‑ The Knott Laboratory aims to identify rationally guided therapeutic strategies to halt disease progression. Li Lab ‑ The Li Lab specializes in the development of novel MRI techniques to address the research and clinical needs of cardiovascular imaging. Ljubimov Lab ‑ The Ljubimov Laboratory is focused on diabetic eye disease. Our goal is to unravel human stem cell alterations in diabetic eye disease and their impact on its development, in order to restore stem cell functions for future clinical translation. Martins Lab ‑ Find out more about the research in the Martins Laboratory as it focuses on the molecular regulation of immune responses, particularly the mechanisms regulating T lymphocyte function at Cedars-Sinai Medical Center in Los Angeles. Medina Kauwe Lab ‑ The Medina-Kauwe's Laboratory utilizes the cell binding, membrane penetration and intracellular trafficking functions of pathogen proteins to develop novel cell-targeted nanotherapeutics. Murali Lab ‑ Find out more about the research at the Murali laboratory and their focus on defining the molecular basis of drug resistance mechanisms, cancer metastasis, and on developing new targeted therapeutic drugs. Noval Rivas Lab ‑ The Noval Rivas Laboratory works to understand how intestinal microbiome and mucosal immune responses influence the severity of Kawasaki disease. Panopoulos Lab ‑ The Panopoulos Laboratory led by Athanasia Panopoulos, focuses on utilizing human somatic cell reprogramming to identify and target novel embryonic mechanisms that are exploited in cancer. Riera Lab ‑ The Riera Laboratory studies the role of central and peripheral sensory neural circuits in metabolic health and aging. S Wang Lab ‑ The primary goal of the S. Wang Laboratory is to understand and develop treatments for degenerative retinal diseases. Saghizadeh Ghiam Lab ‑ The Saghizadeh Ghiam Lab studies molecular corneal defects to restore stem cell function for clinical use. Sareen Lab ‑ The Sareen Laboratory at Cedars-Sinai studies cellular signaling and mechanisms of failure in many neurodegenerative disorders. Sharma Lab ‑ The Sharma Research Laboratory, led Arun Sharma, PhD, focuses on the application of human induced pluripotent stem cells (hiPSCs) for modeling cardiovascular diseases in-vitro. Silm Lab ‑ The Silm Laboratory led by Katlin Silm, PhD focuses on the regulation of neurotransmitter release at the presynaptic compartment, critical for information processing in brain circuits. Svendsen Lab ‑ The Svendsen Laboratory studies neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), Huntington's disease (HD), spinal muscular atrophy (SMA), Parkinson's disease (PD) and Allan-Herndon-Dudley syndrome (AHDS) using stem cells as a disease treatment, as well as a tool for modeling these diseases in vitro. Underhill Lab ‑ The Underhill Laboratory is focused on understanding the molecular mechanisms by which some white blood cells, called macrophages and dendritic cells, recognize microbial pathogens and direct inflammation. Vujkovic‑Cvijin Lab ‑ The Vujkovic-Cvijin Lab, led by Ivan Vujkovic-Cvijin investigates how human gut microbes influence inflammatory diseases. Wolf Lab ‑ The Wolf Laboratory led by Andrea J. Wolf, PhD, studies the cross-talk between the innate immune system of the cell and how the metabolism in phagocytic cells determines the degree and duration of the inflammatory signals. ...view more