Abstract
Abstract Magnetic Resonance Imaging (MRI) plays a pivotal role in distinguishing between necrotic neoplastic lesions and abscesses, two conditions that can present similarly on conventional imaging sequences. Misdiagnosis of these conditions could lead to inappropriate management, as the treatment strategies for each differ significantly. This study explores the utility of multiparametric MRI, combining conventional imaging sequences with advanced functional imaging techniques, to improve the accuracy of this differentiation. We analyzed the MRI features of necrotic tumors and abscesses in 50 patients using Diffusion-Weighted Imaging (DWI), Dynamic Contrast-Enhanced MRI (DCE-MRI), and Magnetic Resonance Spectroscopy (MRS). Our results demonstrated that the combination of these advanced imaging techniques significantly improved diagnostic accuracy. Multiparametric MRI achieved 92% sensitivity and 89% specificity for differentiating necrotic neoplastic lesions from abscesses, outperforming conventional MRI (68% sensitivity, 70% specificity). The inclusion of DWI, DCE-MRI, and MRS enhanced lesion characterization by assessing diffusion, perfusion, and metabolic features, thereby providing more reliable differentiation than structural imaging alone. These findings suggest that multiparametric MRI can be a powerful tool for improving diagnostic precision in distinguishing these clinically important lesions, thereby aiding in appropriate management and treatment decisions.
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