Targeting Methods: A Short Review Including Rationale, Goal, Causes, Strategies for Targeting

Abstract

A type of intelligent drug delivery device known as targeted drug delivery is remarkable at getting the drug to the patient. While the targeted release system releases the medicine in a dose form, the conventional drug delivery method involves the drug being absorbed through a biological membrane. The enhancement of pharmaceutical action, the absence of negative side effects, and the reduction of the supplied dose are just a few of the advantages that targeted drug delivery systems have over conventional ones. The basic goal of a targeted drug delivery system is to ensure that the therapeutic agent only acts on sick organs while avoiding harming healthy ones, particularly when treating cancer with chemotherapeutic drugs. Different carriers that keep and deliver the intact drug to a chosen organ or tissue might be used to target drugs. Various carriers, including nanotubes and nanowires, nanoshells, quantum dots, nanopores, gold nanoparticles, dendrimers, noisome, ufasomes, virosomes, cubosomes, nanobots, and transferosomes, can be utilized for drug targeting. Targeting drugs can be done through a variety of techniques, including passive, inverse, active, ligand-mediated, physical, dual, and double targeting. The medicinal substance can be delivered to a specific spot with the help of medication targeting, which prevents toxicity in other organs. Targeted drug delivery is a cutting-edge technique for giving medications to patients in sequences that are specifically designed to increase the concentration of the drug delivered to the targeted body part of interest (organs, tissues, or cells), which enhances treatment effectiveness by lowering