Paper Title
Surfing the p53 network
Article Type
Research Article
Journal
Research Impact Tools
DOI
Publication Info
Volume: 408 | Pages: 307–310
Published On
November, 2000
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Abstract
Tumour-suppressor genes are needed to keep cells under control. Just as a car’s brakes regulate its speed, properly functioning tumour-suppressor genes act as brakes to the cycle of cell growth, DNA replication and division into two new cells. When these genes fail to function properly, uncontrolled growth — a defining feature of cancer cells — ensues.
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