Abstract
The micro-organism-mediated nanoparticle synthesis is of great importance in the nano-field due to its economic viability, higher and easy bioaccumulation and the process can be scaled up relatively easily. The downstream processing and biomass handling are also facilitated. It is also known to occur naturally. In the current study, the biological synthesis of silver nanoparticles (AgNPs) using Bacillus nakamurai sp. (isolated from soil) is reported. The as-synthesized nanoparticles were characterized using X-ray diffraction to confirm AgNP formation. On characterizing the biosynthesized AgNPs with different analyzing tools, the spherical shape of particles with hydrodynamic size 379.2 nm was observed. To the best of our knowledge, this is the first report to establish an antibacterial peel-off facial mask formulation employing biosynthesized AgNPs. The current study has demonstrated the antibacterial activity of the prepared peel-off facial mask formulation against Pseudomonas aeruginosa, Staphylococcus aureus and Propionibacterium acnes. The antibacterial formulation exhibited the lowest susceptibility to all three bacterial strains and the zone of inhibition for the formulations ranged from 8 to 14 Besides, in the case of control formulation, no resistance to the bacterial strains was revealed. Furthermore, the cost estimation of the prepared antibacterial formulation has also been assessed.
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