ORGANIC CULTIVATION OF TURMERIC RHIZOMES AND THEIR PROCESSING FOR IMMUNITY-BOOSTING TABLET FORMULATION

Abstract

Turmeric (Curcuma longa L.) is widely recognized for its potent therapeutic properties, primarily attributed to curcumin, a bioactive compound known for its anti-inflammatory and immune-boosting effects. This study aimed to develop a sustainable and organic approach for cultivating turmeric, extracting curcumin using eco-friendly methods, and formulating it into immunity-boosting tablets. Organic treatments, including vermicompost (10 t/ha), neem cake (500 kg/ha), and mulching, were applied under field conditions to evaluate their effects on rhizome yield and curcumin content. The highest yield (32.4 t/ha) and curcumin content (6.8%) were observed in plots treated with vermicompost + neem cake + mulch. Curcumin was extracted using Natural Deep Eutectic Solvents (NADES), yielding 3.6 g/100 g powder—30% higher than ethanol-based extraction. Tablets were formulated by incorporating piperine (5 mg) to enhance bioavailability. Physical parameters such as hardness, friability, and disintegration time met pharmacopeial standards. Dissolution tests showed that tablets with piperine released 85% of curcumin within 60 minutes, compared to 43% without piperine. Microbial testing confirmed the safety of the formulation, and stability studies over six months demonstrated retention of quality and potency. Statistical analysis (ANOVA, Tukey’s HSD) confirmed significant differences between treatments. This research supports the feasibility of developing effective, stable, and safe herbal nutraceuticals using organically grown turmeric and green processing techniques, providing a valuable model for eco-friendly immunity-boosting product development.