METHANOLIC EXTRACT OF HOMONOIA RETUSA AERIAL PARTS SHOWS ANTI- DIABETIC EFFECT AGAINST STREPTOZOTOCIN INDUCED IN DIABETES RATS

Abstract

To control diabetes mellitus, there must be an adequate supply of insulin. Many initiatives to limit or control have recently been launched. Growing numbers of people are turning to natural blood sugar-lowering remedies. Studies on herbs that can control diabetes have been published in a wide range of journals. Today, herbal medicine, also known as phytomedicine, is the oldest and most widely used type of healthcare practice. The use of these medicinal plants has been documented in writing more than 5000 years ago, in China, India, Greece, Rome and Syria. Homonoia retusa, belongs to family Euphorbiaceae of flower, leaves and stem were collected and dried, then they were grounded into a powder and passed through sieve 60. After being roughly crushed, the powder was extracted with methanol, then fractionated with non-polar to polar solvent and dried. The anti-diabetic activity of Homonoia retusa aerial parts of methanolic extract and its fraction is currently used to investigation. Present studies shown anti-diabetic activity effectiveness is the similar comparable to that of the widely used medication drug i.e. Glipizide, according to the results. Key words: Diabetes, Homonoia retusa, Leaves, Arial parts