FORMULATION AND EVALUATION OF FENUGREEK CHEWING GUM FOR TREATMENT OF THROAT INFECTION

Abstract

Oral drug delivery system is an area of interest for scientist and formulators in past few years to explore at extreme level in various drug delivery systems. The researchers and scientist are focusing on this drug delivery due to feasible and comfortable administration offered by this route to the patient. Therefore drug delivery can be achieved by incorporating medicament in Chewing gum because of higher vascularity in oral mucosa resulting it in a rapid absorption drug into the systemic circulation. Chewing gum is a combination of a water-immiscible phase, known as gum base emulsifiers, antioxidants, softeners, sweeteners, food colourings, flavoring agents, and in case of medicated chewing gum there is an incorporation of active substances in the formulation for getting the desired therapeutic effect. CG can be used in prevention of throat infection, it also prevent the dryness of mouth and help in maintaining oral hygiene. Therefore it can be concluded that oral drug delivery can take superior treatment by this formulation. The main benefit of CG is, it can be taken without water and it reduces the cost of manufacturing when compared with oral liquid preparations. CG with herbal base such as fenugreek can make it as effective as other conventional formulation without any adverse effects.