Abstract
Tobacco smoke contains over 4,000 distinct chemicals that can be harmful to people in various ways. Because nicotine stimulates the production of serotonin, also known as the pleasure substance, in the brain, it is the most addictive of these substances. In many countries, tobacco use is a leading cause of death and a major contributor to a number of chronic diseases. Because of this, there is a greater need to extract nicotine, the most addictive substance, and deliver it to the body in ways other than smoking and burning, such as eating, breathing, or skin contact. Therefore, the term “therapeutic use of nicotine as a smoking cessation aid” refers to the use of nicotine to help you quit smoking. Choline chloride/ethyl alcohol, a deep eutectic solvent, was used in this research to extract the highest purity nicotine (3-(1-methyl-2-pyrrolidinyl) pyridine) from cigarette tobacco. Infrared analyses reveal that nicotine is the fatty substance extracted from cigarette tobacco. Furthermore, the effects of temperature and extraction time on nicotine production were investigated. The maximum nicotine extraction rate was found at 60 min. The maximum nicotine synthesis rate at 70 °C was 8.14%. The purity of the crude extract was 65% at that time, but increased to 98% upon processing.
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