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Paper Title

Computational fluid dynamics modeling of gas dispersion in multi impeller bioreactor

Authors

Ashok Pandey
Ashok Pandey
Savithri Sivaraman
Savithri Sivaraman
Panneerselvam Ranganathan
Panneerselvam Ranganathan

Keywords

  • Computational Fluid Dynamics
  • Gas Dispersion
  • Multi-Impeller Bioreactor
  • Dual Rushton Turbines
  • Hydrodynamic Parameters
  • Fractional Gas Hold-Up
  • Power Consumption
  • Mixing Time
  • Two-Fluid Model
  • MUSIG Model
  • Polydispersed Gas Flow
  • Bioreactor Flow Regimes
  • ANSYS CFX
  • Numerical Simulations
  • Experimental Validation
  • Gas Flow Rate Effect
  • Impeller Speed Optimization
  • Stirred Bioreactor Modeling
  • Bioprocess Engineering
  • Flow Regime Prediction
  • Turbulence Modeling
  • Aeration Efficiency
  • Reactor Scale-Up
  • Multiphase Flow Simulation
  • Industrial Bioreactors
  • CFD Bioreactor Design

Article Type

Research Article

Research Impact Tools

Issue

Volume : 109 | Issue : 6 | Page No : 588-597

Published On

June, 2010

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Abstract

In the present study, experiments have been carried out to identify various flow regimes in a dual Rushton turbines stirred bioreactor for different gas flow rates and impeller speeds. The hydrodynamic parameters like fractional gas hold-up, power consumption and mixing time have been measured. A two fluid model along with MUSIG model to handle polydispersed gas flow has been implemented to predict the various flow regimes and hydrodynamic parameters in the dual turbines stirred bioreactor. The computational model has been mapped on commercial solver ANSYS CFX. The flow regimes predicted by numerical simulations are validated with the experimental results. The present model has successfully captured the flow regimes as observed during experiments. The measured gross flow characteristics like fractional gas hold-up, and mixing time have been compared with numerical simulations. Also the effect of gas flow rate and impeller speed on gas hold-up and power consumption have been investigated.

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