Association for Research in Vision and Ophthalmology (ARVO)
1552-5783
Monthly
4.4
0146-0404
1962
2402212926
United States
English
YES
iovs@arvo.org
Investigative Ophthalmology & Visual Science (IOVS), published online several times a month, is an official journal of the Association for Research in Vision and Ophthalmology (ARVO), an international organization whose purpose is to advance research worldwide into understanding the visual system and preventing, treating and curing its disorders. Included are original contributions that report clinical or laboratory hypothesis-based research with statistically valid results that clearly advance our knowledge of normal or abnormal processes impacting the visual system. For purely descriptive research, we will consider well-designed studies that provide novel or important insight into the structure and/or function of the visual system (normal or pathological). Subjects cover the 13 sections represented by ARVO's membership and the 3 ARVO cross-sectional groups. Short updates on notable new developments in important research areas are also published, but only by invitation. Summaries of meetings/symposia and general review articles are not considered. The journal was established as an official publication of the Association for Research in Ophthalmology (later renamed the Association for Research in Vision and Ophthalmology). The first issue of Investigative Ophthalmology was published in January 1962, with Bernard Becker, MD, as the Executive Editor. The title was changed to Investigative Ophthalmology & Visual Science in 1977.[2] Abstracts from the ARVO Annual Meeting have been published as an issue of IOVS since 1977.[2] Also in 1977, IOVS was accepted for inclusion in Index Medicus (and later in MEDLINE) and PubMed. IOVS was first published online in 1999, with scanned back content being made available online in 2005. The last print issue was published in 2009, and the journal is now published online only.[2] In January 2016, IOVS ended its subscription program and became open access.[3] All content is freely available to read, and content published 2016-onward is freely available for reuse under either the Creative Commons Attribution-NonCommercial-NoDerivatives license or Creative Commons Attribution license.
Purpose.: Aqueous humor inflow falls 50% during sleeping hours without proportional fall in IOP, partly reflecting reduced outflow facility. The mechanisms underlying outflow facility cyclin...
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