Epigenomics (Epigenomics)

Biological entities are extremely plastic, i.e. they manage to adapt their phenotype in response to environmental and physiological cues. The cellular mechanisms enabling this phenotypic plasticity are studied by the discipline of Epigenetics. “Epigenetics” describes all heritable phenotypic alterations which are not due to changes in the primary DNA sequence. “Epigenomics” refers to genome-wide studies of epigenetic alterations. The advent of numerous epigenetic and epigenomic strategies has emerged to comprehensively investigate DNA methylation variations and chromatin modifications across the genome – two mechanisms that are at the core of epigenomic research. With the creation of the Human Epigenome Project, many research groups have joined forces to further elucidate and exploit new technologies to better understand the basis of normal development and human disease. Emerging evidence suggests that epigenetic and epigenomic alterations are key drivers of disease initiation and progression for many complex diseases including cancer. Epigenetic treatment options and epigenetic tests are likely to be used in the near future to develop personalised therapies. Diagnostic products based on epigenetic changes have been approved as biomarkers by regulatory agencies and many more are under development, and several epigenetic treatments are being tested in clinical trials. Epigenomics provides the forum to address the rapidly progressing research developments in this ever-expanding field; to report on the major challenges ahead and critical advances that are propelling the science forward. The journal delivers this information in concise, at-a-glance article formats – invaluable to a time-constrained community.

Epigenomics (Epigenomics) is :-

• International, Peer-Reviewed, Open Access, Refereed, Cancer epigenetics, Genome-wide epigenetic analyses, Bioinformatic technologies in epigenomics, Environmental epigenetics, Epigenetic mechanisms, Genomic imprinting, Population-scale epigenetic studies, Personalised epigenetic approaches, computational approaches , Online or Print , Semi-monthly Journal

• UGC Approved, ISSN Approved: P-ISSN P-ISSN: 1750-1911, E-ISSN: 1750-192X, Established: 2009, Impact Factor: 3.0
• Provides Crossref DOI

• Not indexed in Scopus, WoS, DOAJ, PubMed, UGC CARE