John Wiley & Sons Ltd
+4
2059-7983
Monthly
2.2
2016
3019755982
United States
English
YES
SJR
andrew.allen@nist.gov
The High-Pressure Freezing Laboratory for Macromolecular Crystallography (HPMX) at the ESRF allows the preparation of gas derivatives of macromolecular crystals suitable for X-ray diffraction data collection on macromolecular crystallography beamlines. Information obtained from pressurized crystals and/or gas-derivatized structures enables the improved understanding of specific issues in structural biology, such as the internal functional architecture of proteins, the interactions and reactivity of gases with macromolecules and functional structural changes including ligand-binding processes.
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